Join the Mate Health Physician Network
Whether for fertility evaluation or post-vasectomy confirmation, Mate Health offers accurate, private, and clinically validated semen analysis, enabling timely and informed clinical decisions.
While physicians refer many consumers, we also serve self-directed men proactively seeking reproductive insight. We’re not here to replace the physician relationship with telehealth. We’re here to enhance your patient’s journey.
When requested, Mate facilitates referrals to board-certified urologists, OB/GYNs, and fertility specialists, connecting your practice with motivated, clinically relevant patients at no cost.
There are no requirements to stock inventory or manage kits; patients won't need to navigate to a website to place an order.
Patients must register before kit shipment, ensuring consistent online patient follow-up. Post-vasectomy kits are shipped 8 weeks after the procedure, with periodic reminders for 30 days after the kit is received.
Your patient sends their sample using our temperature-controlled kit via pre-paid FedEx, guaranteeing delivery to our CLIA-certified laboratory by 10:30 a.m. the following day.
Mate Health provides a comprehensive semen analysis report, securely accessible through a portal for both providers and patients, within 1-2 business days of sample receipt at our laboratory.
Mate Health's Test Menu
We offer a comprehensive menu of scientifically advanced at-home semen analysis tests for your patients.
Includes Mate Health's Complete Semen Analysis with DNA Fragmentation.
Clinical Utility:
- Provides additional insight into male fertility potential beyond semen parameters
- Useful in cases of unexplained infertility, recurrent pregnancy loss, or poor ART outcomes
- Can guide decisions regarding use of ICSI, lifestyle changes, or antioxidant therapy
Methodology:
SCD technology offers a more streamlined and visually interpretable approach to assessing sperm DNA fragmentation, using advanced image processing and AI-driven algorithms to precisely measure sperm halos and enhance diagnostic accuracy.
DNA Fragmentation Classification (WHO 6th Edition):
| Category | DNA Fragmentation Status | Interpretation |
|---|---|---|
| No Halo % | High | Poor DNA quality |
| No Halo Degraded % | Very High / Degraded | Severely fragmented/degraded |
| Small Halo % | Moderate | Some DNA fragmentation |
| Medium Halo % | Low | Relatively good DNA integrity |
| Large Halo % | None or Very Low | Healthy, intact DNA |
Mate Health's comprehensive semen analysis provides a detailed assessment of male fertility potential, adhering to WHO 6th Edition standards. The report offers a quantitative and qualitative evaluation across key parameters:
Clinical Utility:
- Identifies male factor infertility
- Guides further diagnostic workup (e.g., hormonal profile, DNA fragmentation, imaging)
- Supports decision-making for fertility treatments (IUI, IVF, ICSI)
- Monitors response to lifestyle, medical, or surgical interventions
Semen Characteristics:
- Volume - Total ejaculate volume (mL)
- Debris / Round Cells - Presence of leukocytes or immature germ cells
Sperm Concentration & Motile Sperm Concentration:
- Concentration - Total sperm concentration per mL
- Sperm Number - Total sperm count in the entire ejaculate
- Motile Sperm Concentration - Total motile sperm per mL
- PR Motile Sperm Concentration - Progressive motile sperm per mL
- Rapid PR Motile Sperm - Fast-progressing sperm count
- Slow PR Motile Sperm Concentration - Slower-progressing sperm concentration
- Functional Sperm Concentration - Sperm with progressive motility and normal morphology
Motility Percentage Metrics:
- Motility - Percentage of motile sperm
- Progressive Motility - % of sperm moving actively forward
- Rapid Progressive - % moving quickly in a straight line
- Slowly Progressive - % with slower forward motion
- Non-Progressive - % moving without forward progression
- Immotile - % not moving
Morphology (Strict Kruger Criteria):
- Normal Morphology - % of sperm with normal structure
Velocity & Functional Assessment:
- Velocity - Average speed (μm/sec) of progressive sperm
- Motile Sperm - Total motile sperm count
- Progressively Motile Sperm - Count of forward-moving sperm
- Functional Sperm - Estimated count of sperm with fertilization potential
Reference Ranges (WHO 6th Edition):
| Semen Parameter | Reference Ranges |
|---|---|
| Volume | ≥ 1.4 mL |
| Concentration | ≥ 16 M/mL |
| Motility | ≥ 42% |
| Progressive Motility | ≥ 30% |
| Non-Progressive | ≥ 1% |
| Immotile | ≥ 20% |
| Strict Morphology (Normal) | ≥ 4% |
| Motile Sperm Concentration | ≥ 6 M/mL |
| PR Motile Sperm Concentration | ≥ 5 M/mL |
| Velocity | ≥ 5 Mic/Sec |
| Sperm Number | ≥ 39M/Ejac |
| Motile Sperm | ≥ 16 M/Ejac |
| Progressively Motile Sperm | ≥ 12 M/Ejac |
Sperm vitality testing is a critical tool for assessing male fertility, measuring the percentage of live, intact sperm in a sample. It helps differentiate viable but immotile sperm from non-viable (dead) sperm, which is particularly useful when motility is low.
Clinical Utility:
- Sperm vitality testing is instrumental in distinguishing true azoospermia from necrozoospermia by determining whether a semen sample lacking motile sperm contains live, immotile sperm cells
- Sperm vitality testing enhances routine semen analysis by providing viability data, especially when motility is borderline or suboptimal
- Sperm vitality testing aids in determining the appropriate timing for repeat semen analysis or the need for immediate fertility intervention based on the extent of sperm viability
Reference Ranges (WHO 6th Edition):
| Semen Parameter | Reference Range |
|---|---|
| % Live | ≥ 54% should be live |
Post-vasectomy semen analysis (PVSA) is an essential diagnostic follow-up to confirm the success of vasectomy by assessing for the presence or absence of sperm in the ejaculate. Accurate PVSA results are critical to confirming sterility and guiding the safe discontinuation of alternative contraceptive methods.
Clinical Utility:
- Post-vasectomy semen analysis confirms procedural success by demonstrating azoospermia or the presence of only rare, non-motile sperm, indicating effective occlusion of the vas deferens
- The results of PVSA play a critical role in guiding contraceptive counseling by determining when it is safe for the patient to discontinue alternative methods of contraception
- The detection of persistent sperm in the ejaculate may indicate vasectomy failure due to recanalization or incomplete occlusion, necessitating further evaluation or potential repeat intervention
Reference Ranges (AUA and WHO 6th Edition):
| Parameter | Reference Range / Notes |
|---|---|
| Motile Sperm (M/mL) | Target: 0.0; Presence indicates potential failure |
| Immotile Sperm (M/mL) | Acceptable if <0.1 M/mL and non-motile |
| Total Sperm (M/mL) | Acceptable if rare and non-motile |
| Motile Sperm (per Ejaculate) | Target: 0.0 |
| Immotile Sperm (per Ejaculate) | Acceptable if <100,000 and non-motile only |
| Total Sperm (per Ejaculate) | Acceptable if <100,000 and non-motile only |
Video imaging captures real-time footage of sperm behavior, motility, and morphology, providing comprehensive visual documentation. This technique is beneficial in evaluating parameters that are challenging to assess through conventional microscopy alone, such as the motility patterns, tail integrity, and sperm DNA fragmentation, which are key in fertility evaluations.
Clinical Utility:
- Video imaging provides detailed tracking of sperm movement, allowing for more accurate motility assessment and detection of subtle motility defects that could affect fertility
- Video analysis offers a clear visualization of sperm structure and chromatin integrity, helping to detect DNA fragmentation and abnormal motility, which impact male fertility
- Video imaging enables real-time evaluation of sperm vitality and precise detection of azoospermia or rare sperm in post-vasectomy analysis, enhancing outcome assessment and patient counseling
Mate Health's clinic portal streamlines your workflow by providing easy access to your patients' testing progress and results.
WHO 6th Edition Guidelines
Mate Health adheres to the WHO 6th Edition (2021) guidelines for semen analysis, while many other vendors still rely on the WHO 5th Edition (2010). Your fertility deserves the most up-to-date science.